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NanoCarrier Co blank sln formulation
Blank Sln Formulation, supplied by NanoCarrier Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/blank+sln+formulation/blank+sln+formulation/pm40571847-195-3-17
Average 90 stars, based on 1 article reviews
blank sln formulation - by Bioz Stars, 2026-09
90/100 stars

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Article Title: Optimized solid lipid nanoparticles for co-delivery of gentamicin and doxycycline: a novel approach to combat intracellular brucella abortus infections.
Article Snippet: Brucellosis, a zoonotic disease caused by bacteria of the genus Brucella, is a significant public health concern globally.. Among the species, Brucella abortus (B. abortus) is particularly responsible for infections in livestock, leading to reproductive disorders, reduced milk production, and economic losses in the agricultural sector (Almuzaini 2023).. In humans, brucellosis is characterized by fever, fatigue, joint pain, and chronic symptoms that severely affect quality of life (Ahangarzadeh et al. 2024).



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The chemical structure of BH (a), particle size (b), and TEM morphology (c) of BH-loaded <t>SLNs.</t> Drug release profiles of BH-loaded SLNs and free BH for 72-h duration time (d)
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The chemical structure of BH (a), particle size (b), and TEM morphology (c) of BH-loaded SLNs. Drug release profiles of BH-loaded SLNs and free BH for 72-h duration time (d)

Journal: AAPS PharmSciTech

Article Title: Enhancing the Antitumor Activity of Berberine Hydrochloride by Solid Lipid Nanoparticle Encapsulation

doi: 10.1208/s12249-014-0112-0

Figure Lengend Snippet: The chemical structure of BH (a), particle size (b), and TEM morphology (c) of BH-loaded SLNs. Drug release profiles of BH-loaded SLNs and free BH for 72-h duration time (d)

Article Snippet: Determination of Particle Size and Zeta Potential The particle size, polydispersity index (PDI), zeta potential of BH-loaded SLNs, and blank SLNs formulation were measured by a zetasizer (ZSP, Malvern, UK).

Techniques:

Characteristics of the  Formulation  of BH/Blank  SLNs

Journal: AAPS PharmSciTech

Article Title: Enhancing the Antitumor Activity of Berberine Hydrochloride by Solid Lipid Nanoparticle Encapsulation

doi: 10.1208/s12249-014-0112-0

Figure Lengend Snippet: Characteristics of the Formulation of BH/Blank SLNs

Article Snippet: Determination of Particle Size and Zeta Potential The particle size, polydispersity index (PDI), zeta potential of BH-loaded SLNs, and blank SLNs formulation were measured by a zetasizer (ZSP, Malvern, UK).

Techniques: Formulation, Zeta Potential Analyzer

a, b MTT assay showed different viabilities of MCF-7, HepG 2, A549, and MCF 10A treated with free BH and BH-loaded SLNs (0–40 μM) at different time points (24, 48 h). Blank SLNs treatment (0–40 μM), free BH (0–40 μM), and free BH spiked with blank SLNs were presented for comparison reference. Data were obtained by at least three times repeated trials

Journal: AAPS PharmSciTech

Article Title: Enhancing the Antitumor Activity of Berberine Hydrochloride by Solid Lipid Nanoparticle Encapsulation

doi: 10.1208/s12249-014-0112-0

Figure Lengend Snippet: a, b MTT assay showed different viabilities of MCF-7, HepG 2, A549, and MCF 10A treated with free BH and BH-loaded SLNs (0–40 μM) at different time points (24, 48 h). Blank SLNs treatment (0–40 μM), free BH (0–40 μM), and free BH spiked with blank SLNs were presented for comparison reference. Data were obtained by at least three times repeated trials

Article Snippet: Determination of Particle Size and Zeta Potential The particle size, polydispersity index (PDI), zeta potential of BH-loaded SLNs, and blank SLNs formulation were measured by a zetasizer (ZSP, Malvern, UK).

Techniques: MTT Assay, Comparison

Clone formation results incubated for 20 days. Cells were treated with 20 and 40 μM coumarin 6 and coumarin6-loaded SLNs, compared with serum-free and blank SLNs

Journal: AAPS PharmSciTech

Article Title: Enhancing the Antitumor Activity of Berberine Hydrochloride by Solid Lipid Nanoparticle Encapsulation

doi: 10.1208/s12249-014-0112-0

Figure Lengend Snippet: Clone formation results incubated for 20 days. Cells were treated with 20 and 40 μM coumarin 6 and coumarin6-loaded SLNs, compared with serum-free and blank SLNs

Article Snippet: Determination of Particle Size and Zeta Potential The particle size, polydispersity index (PDI), zeta potential of BH-loaded SLNs, and blank SLNs formulation were measured by a zetasizer (ZSP, Malvern, UK).

Techniques: Incubation

Cellular uptake images of MCF-7 cells treated with 20 and 40 μM free BH and BH-loaded SLNs (a) and fluorescence values of MCF-7 detected by flow cytometry (b) for 1-, 2-, and 4-h treatment time

Journal: AAPS PharmSciTech

Article Title: Enhancing the Antitumor Activity of Berberine Hydrochloride by Solid Lipid Nanoparticle Encapsulation

doi: 10.1208/s12249-014-0112-0

Figure Lengend Snippet: Cellular uptake images of MCF-7 cells treated with 20 and 40 μM free BH and BH-loaded SLNs (a) and fluorescence values of MCF-7 detected by flow cytometry (b) for 1-, 2-, and 4-h treatment time

Article Snippet: Determination of Particle Size and Zeta Potential The particle size, polydispersity index (PDI), zeta potential of BH-loaded SLNs, and blank SLNs formulation were measured by a zetasizer (ZSP, Malvern, UK).

Techniques: Fluorescence, Flow Cytometry

a–c Cell cycle distributions of MCF-7 cells treated with different solutions (free BH and BH-loaded SLNs) at different concentrations (40 and 20 μM) compared with control and blank SLNs for 48 h. Free BH and BH-loaded SLNs arrested MCF-7 cells at G1/G0 phase and induced significant decrease at S and G2/M phase. Data were expressed as mean ± standard error. *p < 0.05 vs. control

Journal: AAPS PharmSciTech

Article Title: Enhancing the Antitumor Activity of Berberine Hydrochloride by Solid Lipid Nanoparticle Encapsulation

doi: 10.1208/s12249-014-0112-0

Figure Lengend Snippet: a–c Cell cycle distributions of MCF-7 cells treated with different solutions (free BH and BH-loaded SLNs) at different concentrations (40 and 20 μM) compared with control and blank SLNs for 48 h. Free BH and BH-loaded SLNs arrested MCF-7 cells at G1/G0 phase and induced significant decrease at S and G2/M phase. Data were expressed as mean ± standard error. *p < 0.05 vs. control

Article Snippet: Determination of Particle Size and Zeta Potential The particle size, polydispersity index (PDI), zeta potential of BH-loaded SLNs, and blank SLNs formulation were measured by a zetasizer (ZSP, Malvern, UK).

Techniques: Control

Apoptotic morphology in MCF-7 cells treated with free BH and BH-loaded SLNs for 48 h were detected by Hoechst 33342 fluorescent staining with fluorescence microscopy

Journal: AAPS PharmSciTech

Article Title: Enhancing the Antitumor Activity of Berberine Hydrochloride by Solid Lipid Nanoparticle Encapsulation

doi: 10.1208/s12249-014-0112-0

Figure Lengend Snippet: Apoptotic morphology in MCF-7 cells treated with free BH and BH-loaded SLNs for 48 h were detected by Hoechst 33342 fluorescent staining with fluorescence microscopy

Article Snippet: Determination of Particle Size and Zeta Potential The particle size, polydispersity index (PDI), zeta potential of BH-loaded SLNs, and blank SLNs formulation were measured by a zetasizer (ZSP, Malvern, UK).

Techniques: Staining, Fluorescence, Microscopy

Cell apoptosis of MCF-7 cells after treatment of free BH and BH-loaded SLNs at 20- and 40-μM concentrations for 48 h (a) and the histogram of apoptotic degrees (Q2 and Q4 phase) of MCF-7 treated with 20 and 40 μM free BH and BH-loaded SLNs for 48 h (b). Necrotic cells (Q1 Annexin V-FITC-PI+), late apoptotic (Q2 Annexin V-FITC-PI+), live cells (Q3 Annexin V-FITC-PI-), and early apoptotic cells (Q4 Annexin V-FITC + PI-)

Journal: AAPS PharmSciTech

Article Title: Enhancing the Antitumor Activity of Berberine Hydrochloride by Solid Lipid Nanoparticle Encapsulation

doi: 10.1208/s12249-014-0112-0

Figure Lengend Snippet: Cell apoptosis of MCF-7 cells after treatment of free BH and BH-loaded SLNs at 20- and 40-μM concentrations for 48 h (a) and the histogram of apoptotic degrees (Q2 and Q4 phase) of MCF-7 treated with 20 and 40 μM free BH and BH-loaded SLNs for 48 h (b). Necrotic cells (Q1 Annexin V-FITC-PI+), late apoptotic (Q2 Annexin V-FITC-PI+), live cells (Q3 Annexin V-FITC-PI-), and early apoptotic cells (Q4 Annexin V-FITC + PI-)

Article Snippet: Determination of Particle Size and Zeta Potential The particle size, polydispersity index (PDI), zeta potential of BH-loaded SLNs, and blank SLNs formulation were measured by a zetasizer (ZSP, Malvern, UK).

Techniques: